ChEMBL ligand: CHEMBL2113938 (OSM-S-38)
Plasmodium falciparum [ChEMBL: CHEMBL364] This target only has 0 pki data point 1 CHEMBL2113938_lig_chart_1 Plasmodium falciparum Plasmodium falciparum There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364]
ChEMBL	OSM: Inhibition of Plasmodium falciparum 3D7 growth using a SYBR green I fluorescence based assay. Dose response curves were generated comprising of 8 points using a 2-fold serial dilution for the maximum final concentration of 1000 nM. Ralph Group, Bio21.	F	6.69	pIC50	205	nM	IC50	Open Source Malaria Deposition 1. http://malaria.ourexperiment.org
ChEMBL	OSM: Inhibition of Plasmodium falciparum 3D7 growth using a SYBR green I fluorescence based assay. GSK Tres Cantos.	F	7.54	pIC50	29	nM	IC50	Open Source Malaria Deposition 1. http://malaria.ourexperiment.org
ChEMBL	OSM: Late stage gametocytes. IC50 values determined from 21 point dose response curves. Avery Group Griffith.	F	8.4	pIC50	4	nM	IC50	Open Source Malaria Deposition 1. http://malaria.ourexperiment.org
ChEMBL	OSM: Inhibition of Plasmodium falciparum 3D7 growth. IC50 values determined from 21 point dose response curves. Avery Group Griffith.	F	8.7	pIC50	2	nM	IC50	Open Source Malaria Deposition 1. http://malaria.ourexperiment.org

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]