eCF309 [Ligand Id: 9571] activity data from GtoPdb

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  • mechanistic target of rapamycin kinase in Human [GtoPdb: 2109] [UniProtKB: P42345]
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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336]
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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta in Human [GtoPdb: 2155] [UniProtKB: O00329]
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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
mechanistic target of rapamycin kinase in Human [GtoPdb: 2109] [UniProtKB: P42345]
GtoPdb In a biochemical assys using recombinant wild type enzyme. - 7.82 pIC50 15 nM IC50 Medchemcomm (2016) 7: 471-477
GtoPdb In a cell viability assay. - 8.05 pEC50 9 nM EC50 Medchemcomm (2016) 7: 471-477
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336]
GtoPdb In a biochemical assay. - 6.01 pIC50 981 nM IC50 Medchemcomm (2016) 7: 471-477
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta in Human [GtoPdb: 2155] [UniProtKB: O00329]
GtoPdb In a biochemical assay. - 5.74 pIC50 1840 nM IC50 Medchemcomm (2016) 7: 471-477
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736]
GtoPdb In a biochemical assay. - 5.87 pIC50 1340 nM IC50 Medchemcomm (2016) 7: 471-477

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.