LY3009120 [Ligand Id: 8943] activity data from GtoPdb

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  • A-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1933] [UniProtKB: P10398]
Created with Highcharts 10.3.3ValuesChart context menuA-Raf proto-oncogene, serine/threonine kinasepKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • B-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1943] [UniProtKB: P15056]
Created with Highcharts 10.3.3ValuesChart context menuB-Raf proto-oncogene, serine/threonine kinasepKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • Raf-1 proto-oncogene, serine/threonine kinase in Human [GtoPdb: 2184] [UniProtKB: P04049]
Created with Highcharts 10.3.3ValuesChart context menuRaf-1 proto-oncogene, serine/threonine kinasepKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
A-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1933] [UniProtKB: P10398]
GtoPdb - - 7.36 pIC50 44 nM IC50 Cancer Cell (2015) 28: 384-98 [PMID:26343583]
B-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1943] [UniProtKB: P15056]
GtoPdb - - 8.04 pIC50 9.1 nM IC50 Cancer Cell (2015) 28: 384-98 [PMID:26343583]
Raf-1 proto-oncogene, serine/threonine kinase in Human [GtoPdb: 2184] [UniProtKB: P04049]
GtoPdb - - 7.82 pIC50 15 nM IC50 Cancer Cell (2015) 28: 384-98 [PMID:26343583]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.