17-octadecynoic acid [Ligand Id: 8851] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL182310 (17-Octadecynoic Acid, Octadec-17-ynoic acid) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CYP4F2/Cytochrome P450 4F2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3379] [GtoPdb: 1344] [UniProtKB: P78329] | ||||||||
| GtoPdb | - | - | 5.92 | pKi | 1200 | nM | Ki | J Biol Chem (1985) 260: 13023-8 [PMID:2997155] |
| ChEMBL | Inhibition of leukotriene B4 omega-hydroxylase in human polymorphonuclear leukocytes by UV spectroscopy | B | 5.3 | pIC50 | <5000 | nM | IC50 | Bioorg Med Chem Lett (2012) 22: 6185-6189 [PMID:22932312] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
