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ChEMBL ligand: CHEMBL208528 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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CYP2J2/Cytochrome P450 2J2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3491] [GtoPdb: 1332] [UniProtKB: P51589] | ||||||||
ChEMBL | Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cells | B | 6.8 | pKi | 160 | nM | Ki | Bioorg. Med. Chem. Lett. (2006) 16: 2777-2780 [PMID:16495056] |
ChEMBL | Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cells | B | 6.4 | pIC50 | 400 | nM | IC50 | Bioorg. Med. Chem. Lett. (2006) 16: 2777-2780 [PMID:16495056] |
GtoPdb | Measuring CYP2J2-induced inhibition ebastine hydroxylation. | - | 6.8 | pIC50 | 160 | nM | IC50 | Bioorg Med Chem Lett (2006) 16: 2777-80 [PMID:16495056] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]