compound 4 [PMID: 16495056] [Ligand Id: 8832] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL208528 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CYP2J2/Cytochrome P450 2J2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3491] [GtoPdb: 1332] [UniProtKB: P51589] | ||||||||
| ChEMBL | Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cells | B | 6.8 | pKi | 160 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 2777-2780 [PMID:16495056] |
| ChEMBL | Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cells | B | 6.4 | pIC50 | 400 | nM | IC50 | Bioorg Med Chem Lett (2006) 16: 2777-2780 [PMID:16495056] |
| GtoPdb | Measuring CYP2J2-induced inhibition ebastine hydroxylation. | - | 6.8 | pIC50 | 160 | nM | IC50 | Bioorg Med Chem Lett (2006) 16: 2777-80 [PMID:16495056] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
