compound 51 [Crosignani et al., 2011] [Ligand Id: 8777] activity data from GtoPdb and ChEMBL
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
| ChEMBL ligand: CHEMBL2036213 |
|---|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| DP2 receptor/G protein-coupled receptor 44 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5071] [GtoPdb: 339] [UniProtKB: Q9Y5Y4] | ||||||||
| GtoPdb | - | - | 8.16 | pKi | 6.9 | nM | Ki | ACS Med Chem Lett (2011) 2: 938-42 [PMID:24900284] |
| ChEMBL | Displacement of [3HPGD2 from human CRTH2 receptor expressed in CHO cell membrane after 90 mins by scintillation proximity assay | B | 8.16 | pKi | 6.9 | nM | Ki | ACS Med Chem Lett (2011) 2: 938-942 [PMID:24900284] |
| CYP2C8 in Human [GtoPdb: 1325] [UniProtKB: P10632] | ||||||||
| GtoPdb | - | - | 7.37 | pIC50 | 43 | nM | IC50 | ACS Med Chem Lett (2011) 2: 938-42 [PMID:24900284] |
| CYP2C9 in Human [GtoPdb: 1326] [UniProtKB: P11712] | ||||||||
| GtoPdb | - | - | 6.7 | pIC50 | 200 | nM | IC50 | ACS Med Chem Lett (2011) 2: 938-42 [PMID:24900284] |
| CYP2C19 in Human [GtoPdb: 1328] [UniProtKB: P33261] | ||||||||
| GtoPdb | - | - | 7.29 | pIC50 | 51 | nM | IC50 | ACS Med Chem Lett (2011) 2: 938-42 [PMID:24900284] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
