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ChEMBL ligand: CHEMBL3633720 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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GPR139/Probable G-protein coupled receptor 139 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3632455] [GtoPdb: 130] [UniProtKB: Q6DWJ6] | ||||||||
GtoPdb | - | - | 7.62 | pKi | 24 | nM | Ki | Mol Pharmacol (2015) 88: 911-25 [PMID:26349500] |
ChEMBL | Agonist activity at human GPR139 receptor expressed in HEK293 cells assessed as calcium mobilization by FLIPR assay | F | 7.8 | pEC50 | 16 | nM | EC50 | ACS Med Chem Lett (2015) 6: 1015-1018 [PMID:26396690] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]