ChEMBL ligand: CHEMBL236822 (SQ-24798)
Carboxypeptidase B in Pig [ChEMBL: CHEMBL4065] [UniProtKB: P09955] There should be some charts here, you may need to enable JavaScript!
Carboxypeptidase B2 (plasma)/Carboxypeptidase B2 isoform A in Human [ChEMBL: CHEMBL3419] [GtoPdb: 1594] [UniProtKB: Q96IY4] There should be some charts here, you may need to enable JavaScript!
Carboxypeptidase N, polypeptide 1/Carboxypeptidase N, catalytic subunit in Human [ChEMBL: CHEMBL4713] [GtoPdb: 1597] [UniProtKB: P15169] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Carboxypeptidase B in Pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4065] [UniProtKB: P09955]
ChEMBL	Inhibition of porcine pancreatic carboxypeptidase B	B	9.38	pKi	0.42	nM	Ki	J Med Chem (2007) 50: 6095-6103 [PMID:17990866]
ChEMBL	Inhibition of porcine pancreatic carboxypeptidase B	B	8	pIC50	10	nM	IC50	Bioorg Med Chem Lett (2007) 17: 1349-1354 [PMID:17189688]
Carboxypeptidase B2 (plasma)/Carboxypeptidase B2 isoform A in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3419] [GtoPdb: 1594] [UniProtKB: Q96IY4]
ChEMBL	Inhibition of human TAFIa	B	8.4	pKi	4	nM	Ki	J Med Chem (2007) 50: 6095-6103 [PMID:17990866]
GtoPdb	-	-	8.4	pKi	4	nM	Ki	J Med Chem (2007) 50: 6095-103 [PMID:17990866]
ChEMBL	Inhibition of human activated thrombin activatable fibrinolysis inhibitor	B	8.1	pIC50	8	nM	IC50	Bioorg Med Chem Lett (2007) 17: 1349-1354 [PMID:17189688]
Carboxypeptidase N, polypeptide 1/Carboxypeptidase N, catalytic subunit in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4713] [GtoPdb: 1597] [UniProtKB: P15169]
ChEMBL	Inhibition of human plasma carboxypeptidase N	B	8.7	pKi	2	nM	Ki	J Med Chem (2007) 50: 6095-6103 [PMID:17990866]
GtoPdb	-	-	8.7	pKi	2	nM	Ki	J Med Chem (2007) 50: 6095-103 [PMID:17990866]
ChEMBL	Inhibition of human carboxypeptidase N	B	8.7	pIC50	2	nM	IC50	Bioorg Med Chem Lett (2007) 17: 1349-1354 [PMID:17189688]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]