ChEMBL ligand: CHEMBL236822 (SQ-24798)
Carboxypeptidase B in Pig [ChEMBL: CHEMBL4065] [UniProtKB: P09955] There should be some charts here, you may need to enable JavaScript!
Carboxypeptidase B2 (plasma)/Carboxypeptidase B2 isoform A in Human [ChEMBL: CHEMBL3419] [GtoPdb: 1594] [UniProtKB: Q96IY4] There should be some charts here, you may need to enable JavaScript!
Carboxypeptidase N, polypeptide 1/Carboxypeptidase N, catalytic subunit in Human [ChEMBL: CHEMBL4713] [GtoPdb: 1597] [UniProtKB: P15169] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Carboxypeptidase B in Pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4065] [UniProtKB: P09955]
ChEMBL	Inhibition of porcine pancreatic carboxypeptidase B	B	9.38	pKi	0.42	nM	Ki	J Med Chem (2007) 50: 6095-6103 [PMID:17990866]
ChEMBL	Inhibition of porcine pancreatic carboxypeptidase B	B	8	pIC50	10	nM	IC50	Bioorg Med Chem Lett (2007) 17: 1349-1354 [PMID:17189688]
Carboxypeptidase B2 (plasma)/Carboxypeptidase B2 isoform A in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3419] [GtoPdb: 1594] [UniProtKB: Q96IY4]
ChEMBL	Inhibition of human TAFIa	B	8.4	pKi	4	nM	Ki	J Med Chem (2007) 50: 6095-6103 [PMID:17990866]
GtoPdb	-	-	8.4	pKi	4	nM	Ki	J Med Chem (2007) 50: 6095-103 [PMID:17990866]
ChEMBL	Inhibition of human activated thrombin activatable fibrinolysis inhibitor	B	8.1	pIC50	8	nM	IC50	Bioorg Med Chem Lett (2007) 17: 1349-1354 [PMID:17189688]
Carboxypeptidase N, polypeptide 1/Carboxypeptidase N, catalytic subunit in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4713] [GtoPdb: 1597] [UniProtKB: P15169]
ChEMBL	Inhibition of human plasma carboxypeptidase N	B	8.7	pKi	2	nM	Ki	J Med Chem (2007) 50: 6095-6103 [PMID:17990866]
GtoPdb	-	-	8.7	pKi	2	nM	Ki	J Med Chem (2007) 50: 6095-103 [PMID:17990866]
ChEMBL	Inhibition of human carboxypeptidase N	B	8.7	pIC50	2	nM	IC50	Bioorg Med Chem Lett (2007) 17: 1349-1354 [PMID:17189688]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]