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ChEMBL ligand: CHEMBL589645 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Carboxypeptidase B1 (tissue)/Carboxypeptidase B in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2552] [GtoPdb: 1593] [UniProtKB: P15086] | ||||||||
ChEMBL | Inhibition of human pancreatic carboxypeptidase B | B | 7.57 | pKi | 27 | nM | Ki | Bioorg Med Chem Lett (2010) 20: 92-96 [PMID:19954973] |
GtoPdb | - | - | 7.57 | pKi | 27 | nM | Ki | Bioorg Med Chem Lett (2010) 20: 92-6 [PMID:19954973] |
Carboxypeptidase B2 (plasma)/Carboxypeptidase B2 isoform A in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3419] [GtoPdb: 1594] [UniProtKB: Q96IY4] | ||||||||
ChEMBL | Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins | B | 8.46 | pKi | 3.5 | nM | Ki | Bioorg Med Chem Lett (2010) 20: 92-96 [PMID:19954973] |
GtoPdb | - | - | 8.46 | pKi | 3.5 | nM | Ki | Bioorg Med Chem Lett (2010) 20: 92-6 [PMID:19954973] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]