ChEMBL ligand: CHEMBL589645
Carboxypeptidase B1 (tissue)/Carboxypeptidase B in Human [ChEMBL: CHEMBL2552] [GtoPdb: 1593] [UniProtKB: P15086] There should be some charts here, you may need to enable JavaScript!
Carboxypeptidase B2 (plasma)/Carboxypeptidase B2 isoform A in Human [ChEMBL: CHEMBL3419] [GtoPdb: 1594] [UniProtKB: Q96IY4] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Carboxypeptidase B1 (tissue)/Carboxypeptidase B in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2552] [GtoPdb: 1593] [UniProtKB: P15086]
ChEMBL	Inhibition of human pancreatic carboxypeptidase B	B	7.57	pKi	27	nM	Ki	Bioorg Med Chem Lett (2010) 20: 92-96 [PMID:19954973]
GtoPdb	-	-	7.57	pKi	27	nM	Ki	Bioorg Med Chem Lett (2010) 20: 92-6 [PMID:19954973]
Carboxypeptidase B2 (plasma)/Carboxypeptidase B2 isoform A in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3419] [GtoPdb: 1594] [UniProtKB: Q96IY4]
ChEMBL	Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins	B	8.46	pKi	3.5	nM	Ki	Bioorg Med Chem Lett (2010) 20: 92-96 [PMID:19954973]
GtoPdb	-	-	8.46	pKi	3.5	nM	Ki	Bioorg Med Chem Lett (2010) 20: 92-6 [PMID:19954973]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]