compound 20 [PMID: 12372533] [Ligand Id: 8555] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL107656 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| chymotrypsin C/Chymotrypsin C in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2386] [GtoPdb: 2341] [UniProtKB: Q99895] | ||||||||
| GtoPdb | - | - | 7.3 | pKi | 50 | nM | Ki | Bioorg Med Chem Lett (2002) 12: 3199-202 [PMID:12372533] |
| ChEMBL | Inhibitory concentration against Human pancreatic Serine protease chymotrypsin | B | 7.3 | pIC50 | 50 | nM | IC50 | Bioorg Med Chem Lett (2002) 12: 3199-3202 [PMID:12372533] |
| elastase, neutrophil expressed/Leukocyte elastase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL248] [GtoPdb: 2358] [UniProtKB: P08246] | ||||||||
| ChEMBL | Inhibitory concentration against Human leukocyte Elastase | B | 6.1 | pIC50 | 800 | nM | IC50 | Bioorg Med Chem Lett (2002) 12: 3199-3202 [PMID:12372533] |
| NS3 in Hepatitis C virus (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1293269] [UniProtKB: A3EZJ3] | ||||||||
| ChEMBL | Binding affinity against Hepatitis C virus NS3 protease | B | 8.22 | pKi | 6 | nM | Ki | Bioorg Med Chem Lett (2002) 12: 3199-3202 [PMID:12372533] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
