ChEMBL ligand: CHEMBL2381669
kallikrein related peptidase 3/Prostate specific antigen in Human [ChEMBL: CHEMBL2099] [GtoPdb: 2373] [UniProtKB: P07288] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
kallikrein related peptidase 3/Prostate specific antigen in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2099] [GtoPdb: 2373] [UniProtKB: P07288]
ChEMBL	Inhibition of PSA (unknown origin) in RPMI in presence of 1% fetal bovine serum, 1% penicillin/streptomycin, 1% L-glutamine	B	6.16	pKi	699	nM	Ki	J Med Chem (2013) 56: 4224-4235 [PMID:23692593]
ChEMBL	Inhibition of PSA (unknown origin) in female plasma	B	6.22	pKi	604	nM	Ki	J Med Chem (2013) 56: 4224-4235 [PMID:23692593]
ChEMBL	Inhibition of PSA (unknown origin) in RPMI in presence of 1% fetal bovine serum	B	6.85	pKi	142	nM	Ki	J Med Chem (2013) 56: 4224-4235 [PMID:23692593]
ChEMBL	Inhibition of PSA (unknown origin) in RPMI	B	7.12	pKi	75	nM	Ki	J Med Chem (2013) 56: 4224-4235 [PMID:23692593]
GtoPdb	PSA isolated from human seminal plasma.	-	7.14	pKi	72	nM	Ki	J Med Chem (2013) 56: 4224-35 [PMID:23692593]
ChEMBL	Inhibition of human seminal fluid PSA using Mu-SRKSQQY-AMC as substrate measured for 30 mins by fluorescence assay	B	7.14	pKi	72.29	nM	Ki	J Med Chem (2013) 56: 4224-4235 [PMID:23692593]
ChEMBL	Inhibition of PSA (unknown origin) in 50 mM TRIS.HCL and 100 mM NaCl buffer at pH 7.8	B	7.14	pKi	72	nM	Ki	J Med Chem (2013) 56: 4224-4235 [PMID:23692593]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]