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ChEMBL ligand: CHEMBL429844 (Gl-1001, GL1001, MLN-4760, Ore-1001, Ore1001, ORE1001, ORE-1001 FREE ACID) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Angiotensin-converting enzyme 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3736] [GtoPdb: 1614] [UniProtKB: Q9BYF1] | ||||||||
ChEMBL | Inhibition of ACE2 | B | 9.36 | pIC50 | 0.44 | nM | IC50 | Bioorg Med Chem Lett (2008) 18: 1681-1687 [PMID:18243695] |
ChEMBL | Inhibition of ACE2 | B | 9.36 | pIC50 | 0.44 | nM | IC50 | J Med Chem (2008) 51: 2216-2226 [PMID:18324760] |
ChEMBL | Inhibition of ACE2 (unknown origin) | B | 9.36 | pIC50 | 0.44 | nM | IC50 | J Med Chem (2020) 63: 1978-1995 [PMID:32030982] |
GtoPdb | - | - | 9.36 | pIC50 | 0.44 | nM | IC50 | J Med Chem (2008) 51: 2216-26 [PMID:18324760] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]