moxetumomab pasudotox [Ligand Id: 7675] activity data from GtoPdb and ChEMBL
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
| ChEMBL ligand: CHEMBL1743043 (CAT-8015, HA-22, HA22, Lumoxiti, Moxetumomab pasudotox, Moxetumomab pasudotox tdfk, Moxetumomab pasudotox-tdfk) |
|---|
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CD22 in Human [GtoPdb: 2786] [UniProtKB: P20273] | ||||||||
| GtoPdb | - | - | 8.22 | pKd | 6 | nM | Kd |
J Clin Oncol (2012) 30: 1822-8 [PMID:22355053]; Clin Cancer Res (2011) 17: 6398-405 [PMID:22003067]; WO2003027135. Mutated anti-cd22 antibodies with increased affinity to cd22-expressing leukemia cells. (2003) |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
