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ChEMBL ligand: CHEMBL464925 ((8E,11E,14E)-Anacardic Acid) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Glyceraldehyde-3-phosphate dehydrogenase, glycosomal in Trypanosoma cruzi (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5926] [UniProtKB: P22513] | ||||||||
ChEMBL | Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry | B | 4.42 | pIC50 | 38000 | nM | IC50 | Bioorg Med Chem (2009) 17: 2476-2482 [PMID:19254846] |
E1A binding protein p300 in Human [GtoPdb: 2735] [UniProtKB: Q09472] | ||||||||
GtoPdb | - | - | 5.3 | pIC50 | 5000 | nM | IC50 | J Biol Chem (2003) 278: 19134-40 [PMID:12624111] |
lysine acetyltransferase 2B in Human [GtoPdb: 2737] [UniProtKB: Q92831] | ||||||||
GtoPdb | - | - | 5.07 | pIC50 | 8500 | nM | IC50 |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]