adrenomedullin [Ligand Id: 697] activity data from GtoPdb

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  • CGRP receptor in Mouse [GtoPdb: 48]
  • CGRP receptor in Rat [GtoPdb: 48]
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  • AM1 receptor in Mouse [GtoPdb: 49]
  • AM1 receptor in Rat [GtoPdb: 49]
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  • AM2 receptor in Mouse [GtoPdb: 50]
  • AM2 receptor in Rat [GtoPdb: 50]
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  • ACKR3 in Rat [GtoPdb: 80] [UniProtKB: O89039]
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  • GPR182 in Rat [GtoPdb: 146] [UniProtKB: P31392]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CGRP receptor in Mouse [GtoPdb: 48]
GtoPdb - - 7.6 pIC50 - - - Biochem Pharmacol (2003) 66: 2107-15 [PMID:14609735]
CGRP receptor in Rat [GtoPdb: 48]
GtoPdb - - 8.8 pIC50 - - - Mol Cell Endocrinol (2000) 162: 35-43 [PMID:10854696];
Eur J Neurosci (2001) 14: 618-28 [PMID:11556887]
AM1 receptor in Mouse [GtoPdb: 49]
GtoPdb - - 8 pIC50 - - - Biochem Pharmacol (2003) 66: 2107-15 [PMID:14609735]
AM1 receptor in Rat [GtoPdb: 49]
GtoPdb - - 9.3 pIC50 - - - Mol Cell Endocrinol (2000) 162: 35-43 [PMID:10854696];
Endocrinology (1999) 140: 2883-90 [PMID:10342881];
FEBS Lett (2000) 471: 156-60 [PMID:10767413];
Eur J Neurosci (2001) 14: 618-28 [PMID:11556887]
AM2 receptor in Mouse [GtoPdb: 50]
GtoPdb - - 8.2 pIC50 - - - Biochem Pharmacol (2003) 66: 2107-15 [PMID:14609735]
AM2 receptor in Rat [GtoPdb: 50]
GtoPdb - - 8.2 pIC50 - - - Mol Cell Endocrinol (2000) 162: 35-43 [PMID:10854696]
ACKR3 in Rat [GtoPdb: 80] [UniProtKB: O89039]
GtoPdb - - 7 pEC50 100 nM EC50 Biochem Biophys Res Commun (1995) 217: 832-8 [PMID:8554605]
GPR182 in Rat [GtoPdb: 146] [UniProtKB: P31392]
GtoPdb - - 8.15 pEC50 7 nM EC50 J Biol Chem (1995) 270: 25344-7 [PMID:7592696]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.