ChEMBL ligand: CHEMBL1395 (Android, Plex hormone, RU 24400, Testovis, CDB-110, Oxandrolone impurity, methyltestosterone-, Metandren, Methyltestosterone, L-589.372, Oreton methyl, Oreton, U-2842, Android 5, RU-24400, Android 10, L 589.372, Perandren, Methitest, L-589372, Virilon, Methyltestosterone ciii, Potensan fte, NSC-9701, Testred, NSC-139965, 17-methyltestosterone, Metiltestosterona, Android 25)
Androgen receptor in Human [GtoPdb: 628] [UniProtKB: P10275] Androgen receptor in Rat [ChEMBL: CHEMBL3072] [GtoPdb: 628] [UniProtKB: P15207] There should be some charts here, you may need to enable JavaScript!
Glucocorticoid receptor in Human [ChEMBL: CHEMBL2034] [GtoPdb: 625] [UniProtKB: P04150] There should be some charts here, you may need to enable JavaScript!
Progesterone receptor in Bovine [ChEMBL: CHEMBL1909044] [UniProtKB: Q690N0] There should be some charts here, you may need to enable JavaScript!
Sex hormone-binding globulin in Human [ChEMBL: CHEMBL3305] [UniProtKB: P04278] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Androgen receptor in Human [GtoPdb: 628] [UniProtKB: P10275]
GtoPdb	22Rv1 human prostate cells transfected with hAR and luciferase reporter plasmid driven by the androgen response element.	-	9.66	pEC50	0.22	nM	EC50	Eur J Pharmacol (2013) 720: 107-14 [PMID:24177288]
Androgen receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3072] [GtoPdb: 628] [UniProtKB: P15207]
ChEMBL	DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone)	B	8.37	pKi	4.27	nM	Ki	DrugMatrix in vitro pharmacology data
ChEMBL	Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)	B	7.8	pIC50	15.85	nM	IC50	J Med Chem (2005) 48: 5666-5674 [PMID:16134935]
ChEMBL	DRUGMATRIX: Androgen (Testosterone) AR radioligand binding (ligand: [3H] Mibolerone)	B	8.19	pIC50	6.4	nM	IC50	DrugMatrix in vitro pharmacology data
Glucocorticoid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2034] [GtoPdb: 625] [UniProtKB: P04150]
ChEMBL	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	B	6.08	pKi	838	nM	Ki	DrugMatrix in vitro pharmacology data
ChEMBL	DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone)	B	5.73	pIC50	1843	nM	IC50	DrugMatrix in vitro pharmacology data
Progesterone receptor in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1909044] [UniProtKB: Q690N0]
ChEMBL	DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020)	B	7.48	pKi	33	nM	Ki	DrugMatrix in vitro pharmacology data
ChEMBL	DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020)	B	6.6	pIC50	251	nM	IC50	DrugMatrix in vitro pharmacology data
Sex hormone-binding globulin in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3305] [UniProtKB: P04278]
ChEMBL	Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulin	B	8.43	pKd	3.71	nM	Kd	J Med Chem (2008) 51: 2047-2056 [PMID:18330978]

ChEMBL data shown on this page come from version 36:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]