ChEMBL ligand: CHEMBL2171125
eukaryotic translation initiation factor 2 alpha kinase 3/Eukaryotic translation initiation factor 2-alpha kinase 3 in Human [ChEMBL: CHEMBL6030] [GtoPdb: 2017] [UniProtKB: Q9NZJ5] There should be some charts here, you may need to enable JavaScript!
myosin light chain kinase 2 in Human [GtoPdb: 1553] [UniProtKB: Q9H1R3] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
eukaryotic translation initiation factor 2 alpha kinase 3/Eukaryotic translation initiation factor 2-alpha kinase 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6030] [GtoPdb: 2017] [UniProtKB: Q9NZJ5]
GtoPdb	-	-	9.4	pIC50	0.4	nM	IC50	J Med Chem (2012) 55: 7193-207 [PMID:22827572]
ChEMBL	Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylation	B	9.52	pIC50	0.3	nM	IC50	J Med Chem (2012) 55: 7193-7207 [PMID:22827572]
myosin light chain kinase 2 in Human [GtoPdb: 1553] [UniProtKB: Q9H1R3]
GtoPdb	-	-	6.15	pIC50	701	nM	IC50	J Med Chem (2012) 55: 7193-207 [PMID:22827572]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]