HTS01037 [Ligand Id: 6736] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1077990 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| fatty acid binding protein 4/Fatty acid binding protein adipocyte in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2083] [GtoPdb: 2534] [UniProtKB: P15090] | ||||||||
| ChEMBL | Displacement of radiolabeled 1-anilinonaphthalene 8-sulfonic acid from AFABP expressed in Escherichia coli BL21 (DE3) by fluorescence spectrophotometry | B | 6.17 | pKi | 670 | nM | Ki | J Med Chem (2009) 52: 6024-6031 [PMID:19754198] |
| fatty acid binding protein 4 in Mouse [GtoPdb: 2534] [UniProtKB: P04117] | ||||||||
| GtoPdb | - | - | 6.17 | pKi | 670 | nM | Ki | J Med Chem (2009) 52: 6024-31 [PMID:19754198] |
| fatty acid binding protein 5/Fatty acid binding protein epidermal in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3674] [GtoPdb: 2535] [UniProtKB: Q01469] | ||||||||
| ChEMBL | Displacement of radiolabeled 1-anilinonaphthalene 8-sulfonic acid from EFABP expressed in Escherichia coli BL21 (DE3) by fluorescence spectrophotometry | B | 5.47 | pKi | 3400 | nM | Ki | J Med Chem (2009) 52: 6024-6031 [PMID:19754198] |
| fatty acid binding protein 2/Fatty acid binding protein intestinal in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4879] [GtoPdb: 2532] [UniProtKB: P12104] | ||||||||
| ChEMBL | Displacement of radiolabeled 1-anilinonaphthalene 8-sulfonic acid from IFABP expressed in Escherichia coli BL21 (DE3) by fluorescence spectrophotometry | B | 5.18 | pKi | 6570 | nM | Ki | J Med Chem (2009) 52: 6024-6031 [PMID:19754198] |
| fatty acid binding protein 1/Fatty acid-binding protein, liver in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5421] [GtoPdb: 2531] [UniProtKB: P07148] | ||||||||
| ChEMBL | Displacement of radiolabeled 1-anilinonaphthalene 8-sulfonic acid from LFABP expressed in Escherichia coli BL21 (DE3) by fluorescence spectrophotometry | B | 5.09 | pKi | 8170 | nM | Ki | J Med Chem (2009) 52: 6024-6031 [PMID:19754198] |
| fatty acid binding protein 1 in Mouse [GtoPdb: 2531] [UniProtKB: P12710] | ||||||||
| GtoPdb | - | - | 5.09 | pKi | 8170 | nM | Ki | J Med Chem (2009) 52: 6024-31 [PMID:19754198] |
| fatty acid binding protein 3/Fatty acid binding protein muscle in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3344] [GtoPdb: 2533] [UniProtKB: P05413] | ||||||||
| ChEMBL | Displacement of radiolabeled 1-anilinonaphthalene 8-sulfonic acid from HFABP expressed in Escherichia coli BL21 (DE3) by fluorescence spectrophotometry | B | 5.04 | pKi | 9070 | nM | Ki | J Med Chem (2009) 52: 6024-6031 [PMID:19754198] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
