ChEMBL ligand: CHEMBL574003 (HQL-79)
H-PGDS/Hematopoietic prostaglandin D synthase in Human [ChEMBL: CHEMBL5879] [GtoPdb: 1381] [UniProtKB: O60760] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
H-PGDS/Hematopoietic prostaglandin D synthase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5879] [GtoPdb: 1381] [UniProtKB: O60760]
ChEMBL	Competitive inhibition of human HPGDS using PGH2 as substrate	B	5.3	pKi	5000	nM	Ki	Bioorg Med Chem Lett (2021) 34: 127759-127759 [PMID:33383152]
ChEMBL	Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay at 50 uM	B	4.13	pIC50	73900	nM	IC50	J Med Chem (2010) 53: 5536-5548 [PMID:20684598]
ChEMBL	Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay	B	5.42	pIC50	3800	nM	IC50	J Med Chem (2010) 53: 5536-5548 [PMID:20684598]
GtoPdb	-	-	5.5	pIC50	-	-	-	J Biol Chem (2006) 281: 15277-86 [PMID:16547010]
ChEMBL	Inhibition of human H-PGDS expressed in Escherichia coli BL21 assessed as rate of glutathione-chloro-dinitro benzene conjugation	B	5.74	pIC50	1800	nM	IC50	Eur J Med Chem (2010) 45: 447-454 [PMID:19939518]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]