Nωpropyl-L-arginine [Ligand Id: 6525] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL107528 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| NG,NG-Dimethylarginine dimethylaminohydrolase 1/N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6036] [GtoPdb: 1247] [UniProtKB: O94760] | ||||||||
| ChEMBL | Inhibition of human DDAH1 by plate-reader assay | B | 4.05 | pKi | 90000 | nM | Ki | Bioorg Med Chem (2008) 16: 10205-10209 [PMID:19013076] |
| Neuronal NOS/Nitric-oxide synthase, brain in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3048] [GtoPdb: 1251] [UniProtKB: P29476] | ||||||||
| ChEMBL | Inhibition of rat nNOS | B | 6.26 | pKi | 550 | nM | Ki | J Med Chem (2013) 56: 3121-3147 [PMID:23458846] |
| GtoPdb | - | - | 7.2 | pKi | - | - | - | J Med Chem (1997) 40: 3869-70 [PMID:9397167] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
