KC-12615 [Ligand Id: 6507] activity data from GtoPdb

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  • Neutral endopeptidase in Human [GtoPdb: 1611] [UniProtKB: P08473]
Created with Highcharts 10.3.3ValuesChart context menuNeutral endopeptidasepKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • Endothelin-converting enzyme 1 in Human [GtoPdb: 1615] [UniProtKB: P42892]
Created with Highcharts 10.3.3ValuesChart context menuEndothelin-converting enzyme 1pKd HumanpKi HumanpIC50 HumanpEC50 Human01234567Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Neutral endopeptidase in Human [GtoPdb: 1611] [UniProtKB: P08473]
GtoPdb - - 8.4 pIC50 4.2 nM IC50 Life Sci (2012) 90: 733-9 [PMID:22480516]
Endothelin-converting enzyme 1 in Human [GtoPdb: 1615] [UniProtKB: P42892]
GtoPdb - - 5.8 pIC50 1500 nM IC50 Life Sci (2012) 91: 743-8 [PMID:22480515]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.