[3H]PSB-0413 [Ligand Id: 6147] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL369928 (PSB-0413) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| P2Y12 receptor/Purinergic receptor P2Y12 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2001] [GtoPdb: 328] [UniProtKB: Q9H244] | ||||||||
| ChEMBL | Binding affinity to P2Y12 receptor expressed in human platelets from 0.047 to 50 nM | B | 8.34 | pKd | 4.57 | nM | Kd | Bioorg Med Chem Lett (2005) 15: 5450-5452 [PMID:16213725] |
| GtoPdb | - | - | 8.5 | pKd | 3.16 | nM | Kd |
Purinergic Signal (2013) 9: 59-66 [PMID:22892887]; Bioorg Med Chem Lett (2005) 15: 5450-2 [PMID:16213725] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
