ChEMBL ligand: CHEMBL92461
kinase insert domain receptor/Vascular endothelial growth factor receptor 2 in Human [ChEMBL: CHEMBL279] [GtoPdb: 1813] [UniProtKB: P35968] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
kinase insert domain receptor/Vascular endothelial growth factor receptor 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL279] [GtoPdb: 1813] [UniProtKB: P35968]
ChEMBL	Inhibition of KDR by HTRF assay	B	6.73	pIC50	185	nM	IC50	J Med Chem (2008) 51: 3777-3787 [PMID:18557606]
GtoPdb	-	-	7.72	pIC50	19	nM	IC50	Bioorg Med Chem Lett (2002) 12: 3537-41 [PMID:12443771]
ChEMBL	Inhibitory activity at VEGF-2 receptor.	B	7.72	pIC50	19	nM	IC50	Bioorg Med Chem Lett (2002) 12: 2767-2770 [PMID:12217372]
ChEMBL	Inhibition of Vascular endothelial growth factor receptor 2	B	7.72	pIC50	19	nM	IC50	Bioorg Med Chem Lett (2002) 12: 3537-3541 [PMID:12443771]
ChEMBL	Inhibition of human recombinant His-tagged VEGFR2 assessed as infrared absorption by ELISA assay in presence of 20 uM ATP	B	7.72	pIC50	19	nM	IC50	Bioorg Med Chem Lett (2011) 21: 1371-1375 [PMID:21306896]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]