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ChEMBL ligand: CHEMBL414173 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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apelin receptor/Apelin receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1628481] [GtoPdb: 36] [UniProtKB: P35414] | ||||||||
GtoPdb | - | - | 9.5 | pIC50 | - | - | - |
J Biol Chem (2000) 275: 21061-7 [PMID:10777510]; J Neurochem (2003) 84: 1162-1172 [PMID:12603839]; Biochemistry (2003) 42: 10163-8 [PMID:12939143] |
ChEMBL | Agonist activity at APJ receptor (unknown origin) expressed in CHO cells co-expressing with Calphaq16 assessed as calcium mobilization | F | 9.06 | pEC50 | 0.87 | nM | EC50 | Bioorg. Med. Chem. (2014) 22: 2992-2997 [PMID:24755525] |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]