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ChEMBL ligand: CHEMBL97771 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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EPH receptor B2/Ephrin type-B receptor 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3290] [GtoPdb: 1831] [UniProtKB: P29323] | ||||||||
ChEMBL | Equilibrium binding constant for EPH receptor B2 | B | 4.23 | pKd | 58400 | nM | Kd | J Med Chem (2005) 48: 3221-3230 [PMID:15857128] |
ChEMBL | Inhibition of EPH receptor B2 using ELISA | B | 4.07 | pIC50 | 86000 | nM | IC50 | J Med Chem (2005) 48: 3221-3230 [PMID:15857128] |
receptor interacting serine/threonine kinase 2/Serine/threonine-protein kinase RIPK2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5014] [GtoPdb: 2190] [UniProtKB: O43353] | ||||||||
ChEMBL | Inhibition of RIP2 in the presence of 100uM ATP | B | 7.59 | pIC50 | 26 | nM | IC50 | Biochem J (2007) 408: 297-315 [PMID:17850214] |
GtoPdb | - | - | 7.59 | pIC50 | 26 | nM | IC50 | Biochem J (2007) 408: 297-315 [PMID:17850214] |
Tyrosine-protein kinase SRC in Chicken (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3655] [UniProtKB: P00523] | ||||||||
ChEMBL | Inhibition of Src in the presence of 50uM ATP | B | 6.74 | pIC50 | 180 | nM | IC50 | Biochem J (2007) 408: 297-315 [PMID:17850214] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]