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ChEMBL ligand: CHEMBL261491 (Go-6893) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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L-type calcium channel alpha 1C/beta 2A in Rabbit (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL3638171] [UniProtKB: P15381, P54288] | ||||||||
ChEMBL | Inhibition of Cav1.2 calcium current measured using whole cell patch clamp in human HEK293 cells transfected with rabbit L-type calcium channel subunits | F | 4.7 | pIC50 | 20000 | nM | IC50 | IC50 data for the L-type calcium channel extracted from a set of literature articles |
protein kinase C alpha in Human [GtoPdb: 1482] [UniProtKB: P17252] | ||||||||
GtoPdb | - | - | 8.15 | pIC50 | 7 | nM | IC50 | FEBS Lett (1996) 392: 77-80 [PMID:8772178] |
protein kinase C beta in Human [GtoPdb: 1483] [UniProtKB: P05771] | ||||||||
GtoPdb | - | - | 8.15 | pIC50 | 7 | nM | IC50 | FEBS Lett (1996) 392: 77-80 [PMID:8772178] |
protein kinase C gamma in Human [GtoPdb: 1484] [UniProtKB: P05129] | ||||||||
GtoPdb | - | - | 8.22 | pIC50 | 6 | nM | IC50 | FEBS Lett (1996) 392: 77-80 [PMID:8772178] |
protein kinase C delta in Human [GtoPdb: 1485] [UniProtKB: Q05655] | ||||||||
GtoPdb | - | - | 8 | pIC50 | 10 | nM | IC50 | FEBS Lett (1996) 392: 77-80 [PMID:8772178] |
protein kinase C zeta in Human [GtoPdb: 1491] [UniProtKB: Q05513] | ||||||||
GtoPdb | - | - | 7.22 | pIC50 | 60 | nM | IC50 | FEBS Lett (1996) 392: 77-80 [PMID:8772178] |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]