ChEMBL ligand: CHEMBL261491 (Go-6893)
L-type calcium channel alpha 1C/beta 2A in Rabbit [ChEMBL: CHEMBL3638171] [UniProtKB: P15381, P54288] There should be some charts here, you may need to enable JavaScript!
protein kinase D1/Protein kinase C mu in Human [ChEMBL: CHEMBL3863] [GtoPdb: 1489] [UniProtKB: Q15139] There should be some charts here, you may need to enable JavaScript!
protein kinase C alpha in Human [GtoPdb: 1482] [UniProtKB: P17252] There should be some charts here, you may need to enable JavaScript!
protein kinase C beta in Human [GtoPdb: 1483] [UniProtKB: P05771] There should be some charts here, you may need to enable JavaScript!
protein kinase C gamma in Human [GtoPdb: 1484] [UniProtKB: P05129] There should be some charts here, you may need to enable JavaScript!
protein kinase C delta in Human [GtoPdb: 1485] [UniProtKB: Q05655] There should be some charts here, you may need to enable JavaScript!
protein kinase C zeta in Human [GtoPdb: 1491] [UniProtKB: Q05513] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
L-type calcium channel alpha 1C/beta 2A in Rabbit (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL3638171] [UniProtKB: P15381, P54288]
ChEMBL	Inhibition of Cav1.2 calcium current measured using whole cell patch clamp in human HEK293 cells transfected with rabbit L-type calcium channel subunits	F	4.7	pIC50	20000	nM	IC50	IC50 data for the L-type calcium channel extracted from a set of literature articles
protein kinase D1/Protein kinase C mu in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3863] [GtoPdb: 1489] [UniProtKB: Q15139]
ChEMBL	Inhibition of PKD1 (unknown origin)	B	4.7	pIC50	20000	nM	IC50	J Med Chem (2023) 66: 122-139 [PMID:36538005]
protein kinase C alpha in Human [GtoPdb: 1482] [UniProtKB: P17252]
GtoPdb	-	-	8.15	pIC50	7	nM	IC50	FEBS Lett (1996) 392: 77-80 [PMID:8772178]
protein kinase C beta in Human [GtoPdb: 1483] [UniProtKB: P05771]
GtoPdb	-	-	8.15	pIC50	7	nM	IC50	FEBS Lett (1996) 392: 77-80 [PMID:8772178]
protein kinase C gamma in Human [GtoPdb: 1484] [UniProtKB: P05129]
GtoPdb	-	-	8.22	pIC50	6	nM	IC50	FEBS Lett (1996) 392: 77-80 [PMID:8772178]
protein kinase C delta in Human [GtoPdb: 1485] [UniProtKB: Q05655]
GtoPdb	-	-	8	pIC50	10	nM	IC50	FEBS Lett (1996) 392: 77-80 [PMID:8772178]
protein kinase C zeta in Human [GtoPdb: 1491] [UniProtKB: Q05513]
GtoPdb	-	-	7.22	pIC50	60	nM	IC50	FEBS Lett (1996) 392: 77-80 [PMID:8772178]

ChEMBL data shown on this page come from version 35:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]