ChEMBL ligand: CHEMBL190662 (Cyclohexanecarboxylic Acid Pentadecylamide, N-Pentadecylcyclohexanecarboxamide)
N-Acylethanolamine acid amidase/N-acylsphingosine-amidohydrolase in Human [ChEMBL: CHEMBL4349] [GtoPdb: 1402] [UniProtKB: Q02083] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
N-Acylethanolamine acid amidase/N-acylsphingosine-amidohydrolase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4349] [GtoPdb: 1402] [UniProtKB: Q02083]
ChEMBL	Inhibition of human recombinant NAAA expressed in human HEK293 cells assessed as conversion of [1,2-14C]palmitoylethanolamine to [1,2-14C]ethanolamine by liquid scintillation counting	B	4.77	pIC50	17000	nM	IC50	Bioorg Med Chem Lett (2010) 20: 1210-1213 [PMID:20022504]
GtoPdb	-	-	5.3	pIC50	5010	nM	IC50	Biochem J (2004) 379: 99-106 [PMID:14686878]
ChEMBL	Inhibitory concentration against N-palmitoylethanolamine acid amidase	B	5.35	pIC50	4500	nM	IC50	J Med Chem (2005) 48: 5059-5087 [PMID:16078824]
ChEMBL	Inhibition of NAAA	B	5.35	pIC50	4500	nM	IC50	Bioorg Med Chem Lett (2010) 20: 1210-1213 [PMID:20022504]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]