ChEMBL ligand: CHEMBL360052
GlyT1/Glycine transporter 1 in Human [ChEMBL: CHEMBL2337] [GtoPdb: 935] [UniProtKB: P48067] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
GlyT1/Glycine transporter 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2337] [GtoPdb: 935] [UniProtKB: P48067]
ChEMBL	Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter	B	6.49	pIC50	320	nM	IC50	Bioorg Med Chem Lett (2004) 14: 4027-4030 [PMID:15225720]
ChEMBL	Inhibition of GlyT1B (unknown origin)	B	6.9	pIC50	125.89	nM	IC50	J Med Chem (2020) 63: 3834-3867 [PMID:31774679]
GtoPdb	Inhibition of glycine uptake by hGlyT1b stably expressed in CHO cells.	-	8.2	pIC50	6.3	nM	IC50	Bioorg Med Chem Lett (2001) 11: 2007-9 [PMID:11454468]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]