[3H]hemicholinium-3 [Ligand Id: 4493] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL197027 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| Vesicular acetylcholine transporter in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4767] [GtoPdb: 1013] [UniProtKB: Q16572] | ||||||||
| ChEMBL | Percent inhibition against Acetylcholine transporter at 1 uM | B | 7.92 | pIC50 | 12 | nM | IC50 | J Med Chem (2005) 48: 6887-6896 [PMID:16250647] |
| CHT in Human [GtoPdb: 914] [UniProtKB: Q9GZV3] | ||||||||
| GtoPdb | - | - | 8.4 | pKd | 4 | nM | Kd | |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
