M15 [Ligand Id: 3896] activity data from GtoPdb

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  • GAL1 receptor in Human [GtoPdb: 243] [UniProtKB: P47211]
  • GAL1 receptor in Mouse [GtoPdb: 243] [UniProtKB: P56479]
  • GAL1 receptor in Rat [GtoPdb: 243] [UniProtKB: Q62805]
Created with Highcharts 10.3.3ValuesChart context menuGAL1 receptorpKd HumanpKi HumanpIC50 HumanpEC50 HumanpKd MousepKi MousepIC50 MousepEC50 MousepKd RatpKi RatpIC50 RatpEC50 Rat024681012Highcharts.com
  • GAL2 receptor in Honeybee [GtoPdb: 244]
  • GAL2 receptor in Human [GtoPdb: 244] [UniProtKB: O43603]
  • GAL2 receptor in Mouse [GtoPdb: 244] [UniProtKB: O88854]
  • GAL2 receptor in Rat [GtoPdb: 244] [UniProtKB: O08726]
Created with Highcharts 10.3.3ValuesChart context menuGAL2 receptorpKd HoneybeepKi HoneybeepIC50 HoneybeepEC50 HoneybeepKd HumanpKi HumanpIC50 HumanpEC50 HumanpKd MousepKi MousepIC50 MousepEC50 MousepKd RatpKi RatpIC50 RatpEC50 Rat0246810Highcharts.com
  • GAL3 receptor in Human [GtoPdb: 245] [UniProtKB: O60755]
  • GAL3 receptor in Rat [GtoPdb: 245] [UniProtKB: O88626]
Created with Highcharts 10.3.3ValuesChart context menuGAL3 receptorpKd HumanpKi HumanpIC50 HumanpEC50 HumanpKd RatpKi RatpIC50 RatpEC50 Rat0246810Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GAL1 receptor in Human [GtoPdb: 243] [UniProtKB: P47211]
GtoPdb - - 10.57 pKi 0.03 nM Ki J Pharmacol Exp Ther (1998) 287: 448-56 [PMID:9808667];
Peptides (1998) 19: 1771-81 [PMID:9880084];
Neuropeptides (2005) 39: 143-6 [PMID:15944002]
GtoPdb - - 8.84 pIC50 1.46 nM IC50 Biochem Biophys Res Commun (1997) 233: 823-8 [PMID:9168941];
Brain Res Mol Brain Res (1998) 58: 156-69 [PMID:9685625]
GAL1 receptor in Mouse [GtoPdb: 243] [UniProtKB: P56479]
GtoPdb - - 8.65 pKi 2.24 nM Ki FEBS Lett (1997) 411: 225-30 [PMID:9271210];
J Neurochem (1998) 71: 2252-9 [PMID:9832122]
GAL1 receptor in Rat [GtoPdb: 243] [UniProtKB: Q62805]
GtoPdb - - 9.19 pKi 0.65 nM Ki J Biol Chem (1997) 272: 24612-6 [PMID:9305929];
J Biol Chem (1998) 273: 23321-6 [PMID:9722565];
Mol Pharmacol (1997) 52: 337-43 [PMID:9281594];
Brain Res Mol Brain Res (1995) 34: 179-89 [PMID:8750821]
GtoPdb - - 9 pIC50 1 nM IC50 Biochem Biophys Res Commun (1997) 233: 823-8 [PMID:9168941];
FEBS Lett (1997) 405: 285-90 [PMID:9108306]
GAL2 receptor in Honeybee [GtoPdb: 244]
GtoPdb - - 8.97 pKi 1.07 nM Ki Peptides (1998) 19: 1771-81 [PMID:9880084]
GAL2 receptor in Human [GtoPdb: 244] [UniProtKB: O43603]
GtoPdb - - 8.4 pIC50 4.02 nM IC50 Brain Res Mol Brain Res (1998) 58: 156-69 [PMID:9685625]
GtoPdb - - 9.19 pEC50 0.65 nM EC50 Peptides (1998) 19: 1771-81 [PMID:9880084];
Brain Res Mol Brain Res (1998) 58: 156-69 [PMID:9685625];
Biochem Biophys Res Commun (1998) 243: 474-9 [PMID:9480833]
GAL2 receptor in Mouse [GtoPdb: 244] [UniProtKB: O88854]
GtoPdb - - 8.85 pKi 1.4 nM Ki J Neurochem (1998) 71: 2252-9 [PMID:9832122]
GAL2 receptor in Rat [GtoPdb: 244] [UniProtKB: O08726]
GtoPdb - - 9 pKi 1 nM Ki J Biol Chem (1997) 272: 24612-6 [PMID:9305929];
J Biol Chem (1998) 273: 23321-6 [PMID:9722565];
Mol Pharmacol (1997) 52: 337-43 [PMID:9281594];
J Biol Chem (1997) 272: 31949-52 [PMID:9405385];
J Neurochem (1998) 71: 2252-9 [PMID:9832122];
Neuropeptides (2005) 39: 143-6 [PMID:15944002]
GtoPdb - - 8.32 pIC50 4.8 nM IC50 Brain Res Mol Brain Res (1997) 51: 49-59 [PMID:9427506];
FEBS Lett (1997) 405: 285-90 [PMID:9108306]
GtoPdb - - 6.52 pEC50 300 nM EC50 J Biol Chem (1997) 272: 24612-6 [PMID:9305929]
GAL3 receptor in Human [GtoPdb: 245] [UniProtKB: O60755]
GtoPdb - - 7.4 pKi 39.81 nM Ki J Biol Chem (1998) 273: 23321-6 [PMID:9722565];
Peptides (1998) 19: 1771-81 [PMID:9880084]
GAL3 receptor in Rat [GtoPdb: 245] [UniProtKB: O88626]
GtoPdb - - 7.98 pKi 10.5 nM Ki J Biol Chem (1998) 273: 23321-6 [PMID:9722565];
J Biol Chem (1997) 272: 31949-52 [PMID:9405385];
Neuropeptides (2005) 39: 143-6 [PMID:15944002]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.