galanin [Ligand Id: 3592] activity data from GtoPdb

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  • GAL1 receptor in Human [GtoPdb: 243] [UniProtKB: P47211]
  • GAL1 receptor in Rat [GtoPdb: 243] [UniProtKB: Q62805]
Created with Highcharts 10.3.3ValuesChart context menuGAL1 receptorpKd HumanpKi HumanpIC50 HumanpEC50 HumanpKd RatpKi RatpIC50 RatpEC50 Rat024681012Highcharts.com
  • GAL2 receptor in Human [GtoPdb: 244] [UniProtKB: O43603]
  • GAL2 receptor in Rat [GtoPdb: 244] [UniProtKB: O08726]
Created with Highcharts 10.3.3ValuesChart context menuGAL2 receptorpKd HumanpKi HumanpIC50 HumanpEC50 HumanpKd RatpKi RatpIC50 RatpEC50 Rat0246810Highcharts.com
  • GAL3 receptor in Human [GtoPdb: 245] [UniProtKB: O60755]
  • GAL3 receptor in Rat [GtoPdb: 245] [UniProtKB: O88626]
Created with Highcharts 10.3.3ValuesChart context menuGAL3 receptorpKd HumanpKi HumanpIC50 HumanpEC50 HumanpKd RatpKi RatpIC50 RatpEC50 Rat02468Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GAL1 receptor in Human [GtoPdb: 243] [UniProtKB: P47211]
GtoPdb - - 10.51 pKi 0.03 nM Ki J Pharmacol Exp Ther (1998) 287: 448-56 [PMID:9808667];
Peptides (1998) 19: 1771-81 [PMID:9880084];
Proc Natl Acad Sci USA (1994) 91: 9780-3 [PMID:7524088];
Regul Pept (2001) 102: 15-9 [PMID:11600206]
GtoPdb - - 9.89 pIC50 0.13 nM IC50 Proc Natl Acad Sci USA (2001) 98: 9960-4 [PMID:11481429];
Biochem Biophys Res Commun (1997) 233: 823-8 [PMID:9168941];
Brain Res Mol Brain Res (1998) 58: 156-69 [PMID:9685625]
GAL1 receptor in Rat [GtoPdb: 243] [UniProtKB: Q62805]
GtoPdb - - 9.85 pKi 0.14 nM Ki J Biol Chem (1998) 273: 23321-6 [PMID:9722565];
J Mol Neurosci (1995) 6: 33-41 [PMID:8562318]
GtoPdb - - 10.22 pIC50 0.06 nM IC50 Biochem Biophys Res Commun (1997) 233: 823-8 [PMID:9168941];
FEBS Lett (1997) 405: 285-90 [PMID:9108306]
GAL2 receptor in Human [GtoPdb: 244] [UniProtKB: O43603]
GtoPdb - - 9.07 pKi 0.86 nM Ki Peptides (1998) 19: 1771-81 [PMID:9880084];
Regul Pept (2001) 102: 15-9 [PMID:11600206];
Biochem Biophys Res Commun (1998) 243: 474-9 [PMID:9480833]
GtoPdb - - 9.29 pIC50 0.51 nM IC50 Brain Res Mol Brain Res (1998) 58: 156-69 [PMID:9685625]
GtoPdb - - 9.15 pEC50 0.71 nM EC50 Peptides (1998) 19: 1771-81 [PMID:9880084];
Brain Res Mol Brain Res (1998) 58: 156-69 [PMID:9685625]
GAL2 receptor in Rat [GtoPdb: 244] [UniProtKB: O08726]
GtoPdb - - 8.6 pKi 2.51 nM Ki J Biol Chem (1998) 273: 23321-6 [PMID:9722565]
GtoPdb - - 9 pIC50 1 nM IC50 Brain Res Mol Brain Res (1997) 51: 49-59 [PMID:9427506];
Proc Natl Acad Sci USA (2001) 98: 9960-4 [PMID:11481429];
FEBS Lett (1997) 405: 285-90 [PMID:9108306]
GAL3 receptor in Human [GtoPdb: 245] [UniProtKB: O60755]
GtoPdb - - 7.16 pKi 69.18 nM Ki J Biol Chem (1998) 273: 23321-6 [PMID:9722565];
Peptides (1998) 19: 1771-81 [PMID:9880084]
GtoPdb - - 7.12 pIC50 75 nM IC50 J Neurochem (1998) 71: 2239-51 [PMID:9832121]
GAL3 receptor in Rat [GtoPdb: 245] [UniProtKB: O88626]
GtoPdb - - 7.28 pKi 52.48 nM Ki J Biol Chem (1998) 273: 23321-6 [PMID:9722565]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.