BMS compound 87b [Ligand Id: 3492] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL50593 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CCR3/C-C chemokine receptor type 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3473] [GtoPdb: 60] [UniProtKB: P51677] | ||||||||
| GtoPdb | - | - | 8.1 | pKi | 7.94 | nM | Ki | Bioorg Med Chem Lett (2002) 12: 1785-9 [PMID:12067561] |
| ChEMBL | In vitro C-C chemokine receptor type 3 activity of compound by using eotaxin induced human eosinophil chemotaxis assay | F | 7.7 | pIC50 | 20 | nM | IC50 | Bioorg Med Chem Lett (2002) 12: 1785-1789 [PMID:12067561] |
| ChEMBL | In vitro inhibition if C-C chemokine receptor type 3 (CCR3) using 150p M [125I]-labeled human eotaxin | B | 8.1 | pIC50 | 8 | nM | IC50 | Bioorg Med Chem Lett (2002) 12: 1785-1789 [PMID:12067561] |
| ChEMBL | In vitro inhibition if C-C chemokine receptor type 3 (CCR3) using 150p M [125I]-labeled human eotaxin | B | 8.22 | pIC50 | 6 | nM | IC50 | Bioorg Med Chem Lett (2002) 12: 1785-1789 [PMID:12067561] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
