hexocyclium [Ligand Id: 323] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1201325 (Hexocyclium)
  • M1 receptor in Rat [GtoPdb: 13] [UniProtKB: P08482]
  • This target only has 1 pki data point
  • 8.6
1 CHEMBL1201325_lig_chart_1 M1 receptor Rat
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  • M2 receptor in Human [GtoPdb: 14] [UniProtKB: P08172]
  • This target only has 1 pki data point
  • 7.6
2 CHEMBL1201325_lig_chart_2 M2 receptor Human
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  • M3 receptor in Human [GtoPdb: 15] [UniProtKB: P20309]
  • This target only has 1 pki data point
  • 8.9
3 CHEMBL1201325_lig_chart_3 M3 receptor Human
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  • M4 receptor in Human [GtoPdb: 16] [UniProtKB: P08173]
  • This target only has 1 pki data point
  • 8.3
4 CHEMBL1201325_lig_chart_4 M4 receptor Human
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  • M5 receptor in Human [GtoPdb: 17] [UniProtKB: P08912]
  • This target only has 1 pki data point
  • 8.4
5 CHEMBL1201325_lig_chart_5 M5 receptor Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
M1 receptor in Rat [GtoPdb: 13] [UniProtKB: P08482]
GtoPdb - - 8.6 pKi - - - Mol Pharmacol (1989) 35: 469-76 [PMID:2704370]
M2 receptor in Human [GtoPdb: 14] [UniProtKB: P08172]
GtoPdb - - 7.6 pKi - - - Mol Pharmacol (1989) 35: 469-76 [PMID:2704370]
M3 receptor in Human [GtoPdb: 15] [UniProtKB: P20309]
GtoPdb - - 8.9 pKi - - - Mol Pharmacol (1989) 35: 469-76 [PMID:2704370]
M4 receptor in Human [GtoPdb: 16] [UniProtKB: P08173]
GtoPdb - - 8.3 pKi - - - Mol Pharmacol (1989) 35: 469-76 [PMID:2704370]
M5 receptor in Human [GtoPdb: 17] [UniProtKB: P08912]
GtoPdb - - 8.4 pKi - - - Mol Pharmacol (1989) 35: 469-76 [PMID:2704370]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]