ChEMBL ligand: CHEMBL27246 (3-Phenylacrylic Acid, Cinnamic Acid, (E)-Cinnamic Acid, E-Cinnamic Acid, Trans-Cinnamic Acid)
3-oxoacyl-[acyl-carrier-protein] synthase 3 in Escherichia coli [ChEMBL: CHEMBL1795135] [UniProtKB: C3TDZ2] There should be some charts here, you may need to enable JavaScript!
Beta amyloid A4 protein in Human [ChEMBL: CHEMBL2487] [UniProtKB: P05067] There should be some charts here, you may need to enable JavaScript!
HCA2 receptor/Hydroxycarboxylic acid receptor 2 in Human [ChEMBL: CHEMBL3785] [GtoPdb: 312] [UniProtKB: Q8TDS4] There should be some charts here, you may need to enable JavaScript!
phosphomevalonate kinase in Rat [GtoPdb: 641] [UniProtKB: Q5RK24] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
3-oxoacyl-[acyl-carrier-protein] synthase 3 in Escherichia coli (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1795135] [UniProtKB: C3TDZ2]
ChEMBL	Inhibition of N-terminal His-tagged Escherichia coli FabH expressed in Escherichia coli BL21 (DE3) using [3H]acetyl-coA after 25 mins by liquid scintillation counting	B	4.36	pIC50	43400	nM	IC50	Bioorg Med Chem (2011) 19: 4513-4519 [PMID:21741250]
Beta amyloid A4 protein in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2487] [UniProtKB: P05067]
ChEMBL	Inhibition of human amyloid beta (1 to 42) aggregation after 24 hrs by thioflavin-T fluorescence assay	B	4	pIC50	>100000	nM	IC50	Bioorg Med Chem (2012) 20: 5844-5849 [PMID:22921742]
HCA2 receptor/Hydroxycarboxylic acid receptor 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3785] [GtoPdb: 312] [UniProtKB: Q8TDS4]
ChEMBL	Displacement of [3H]nicotinic acid from human GPR109a receptor expressed in human HEK293T cells by liquid scintillation counting	B	5.31	pKi	4900	nM	Ki	Bioorg Med Chem Lett (2011) 21: 2736-2739 [PMID:21167710]
GtoPdb	-	-	3.62	pEC50	240000	nM	EC50	J Lipid Res (2009) 50: 908-14 [PMID:19136666]
phosphomevalonate kinase in Rat [GtoPdb: 641] [UniProtKB: Q5RK24]
GtoPdb	extracted from rat liver, in vitro assay	-	2.42	pKi	3850000	nM	Ki	Biochem J (1979) 181: 143-51 [PMID:226078]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]