muscarinic toxin 3 [Ligand Id: 313] activity data from GtoPdb

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  • M1 receptor in Human [GtoPdb: 13] [UniProtKB: P11229]
  • This target only has 1 pki data point
  • 7.1
1 _lig_chart_1 M1 receptor Human
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  • M2 receptor in Human [GtoPdb: 14] [UniProtKB: P08172]
  • This target only has 1 pki data point
  • 6
2 _lig_chart_2 M2 receptor Human
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  • M3 receptor in Human [GtoPdb: 15] [UniProtKB: P20309]
  • This target only has 1 pki data point
  • 6
3 _lig_chart_3 M3 receptor Human
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  • M4 receptor in Human [GtoPdb: 16] [UniProtKB: P08173]
  • 8.61
4 _lig_chart_4 M4 receptor Human
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  • M5 receptor in Human [GtoPdb: 17] [UniProtKB: P08912]
  • This target only has 1 pki data point
  • 6
5 _lig_chart_5 M5 receptor Human
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  • α2A-adrenoceptor in Human [GtoPdb: 25] [UniProtKB: P08913]
  • This target only has 1 pki data point
  • 8.3
6 _lig_chart_6 α2A-adrenoceptor Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
M1 receptor in Human [GtoPdb: 13] [UniProtKB: P11229]
GtoPdb - - 7.1 pKi - - - FEBS Lett (1994) 352: 91-4 [PMID:7925952]
M2 receptor in Human [GtoPdb: 14] [UniProtKB: P08172]
GtoPdb - - 6 pKi - - - FEBS Lett (1994) 352: 91-4 [PMID:7925952]
GtoPdb - - 6.3 pA2 - - - J Pharmacol Exp Ther (1999) 288: 164-70 [PMID:9862767]
M3 receptor in Human [GtoPdb: 15] [UniProtKB: P20309]
GtoPdb - - 6 pKi - - - FEBS Lett (1994) 352: 91-4 [PMID:7925952]
M4 receptor in Human [GtoPdb: 16] [UniProtKB: P08173]
GtoPdb - - 8.52 pKi 3 nM Ki Invest Ophthalmol Vis Sci (2018) 59: 2778-2791 [PMID:29860464]
GtoPdb - - 8.7 pKi - - - FEBS Lett (1994) 352: 91-4 [PMID:7925952];
J Pharmacol Exp Ther (1999) 288: 164-70 [PMID:9862767]
M5 receptor in Human [GtoPdb: 17] [UniProtKB: P08912]
GtoPdb - - 6 pKi - - - FEBS Lett (1994) 352: 91-4 [PMID:7925952]
α2A-adrenoceptor in Human [GtoPdb: 25] [UniProtKB: P08913]
GtoPdb - - 8.3 pKi 5 nM Ki Invest Ophthalmol Vis Sci (2018) 59: 2778-2791 [PMID:29860464]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.