ChEMBL ligand: CHEMBL505374 (Zaragozic Acid C)
squalene synthase /Squalene synthetase in Human [ChEMBL: CHEMBL3338] [GtoPdb: 645] [UniProtKB: P37268] squalene synthase /Squalene synthetase in Rat [ChEMBL: CHEMBL3815] [GtoPdb: 645] [UniProtKB: Q02769] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
squalene synthase /Squalene synthetase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3338] [GtoPdb: 645] [UniProtKB: P37268]
ChEMBL	Inhibition of squalene synthase	B	9.52	pIC50	0.3	nM	IC50	J Nat Prod (1996) 59: 52-54
squalene synthase /Squalene synthetase in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3815] [GtoPdb: 645] [UniProtKB: Q02769]
ChEMBL	Inhibition of rat squalene synthase	B	10.35	pKi	0.04	nM	Ki	J Nat Prod (1996) 59: 52-54
GtoPdb	Inhibition of rat squalene synthase	-	10.4	pKi	0.05	nM	Ki	Proc Natl Acad Sci USA (1993) 90: 80-4 [PMID:8419946]; Tetrahedron (1992) 48: 10221-10226
ChEMBL	Inhibition of rat liver squalene synthase by liqiud scintillation counting	B	9.4	pIC50	0.4	nM	IC50	J Nat Prod (1993) 56: 1923-1929 [PMID:8289063]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]