ChEMBL ligand: CHEMBL353882
Liver X receptor-α/LXR-alpha in Human [ChEMBL: CHEMBL2808] [GtoPdb: 602] [UniProtKB: Q13133] There should be some charts here, you may need to enable JavaScript!
GPR183 in Human [GtoPdb: 81] [UniProtKB: P32249] There should be some charts here, you may need to enable JavaScript!
Liver X receptor-β in Human [GtoPdb: 601] [UniProtKB: P55055] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Liver X receptor-α/LXR-alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2808] [GtoPdb: 602] [UniProtKB: Q13133]
ChEMBL	Concentration required for half maximal activity was calculated in human nuclear oxysterol receptor liver X receptor-alpha in LiSA.	B	6.6	pEC50	250	nM	EC50	J Med Chem (2001) 44: 886-897 [PMID:11300870]
GtoPdb	-	-	7.1	pEC50	-	-	-	J Biol Chem (2001) 276: 38378-87 [PMID:11504730]
GPR183 in Human [GtoPdb: 81] [UniProtKB: P32249]
GtoPdb	-	-	5.52	pEC50	3029	nM	EC50	Nature (2011) 475: 519-23 [PMID:21796211]
Liver X receptor-β in Human [GtoPdb: 601] [UniProtKB: P55055]
GtoPdb	-	-	7.15	pEC50	-	-	-	J Biol Chem (2001) 276: 38378-87 [PMID:11504730]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]