ChEMBL ligand: CHEMBL353882
Liver X receptor-α/LXR-alpha in Human [ChEMBL: CHEMBL2808] [GtoPdb: 602] [UniProtKB: Q13133] There should be some charts here, you may need to enable JavaScript!
GPR183 in Human [GtoPdb: 81] [UniProtKB: P32249] There should be some charts here, you may need to enable JavaScript!
Liver X receptor-β in Human [GtoPdb: 601] [UniProtKB: P55055] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Liver X receptor-α/LXR-alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2808] [GtoPdb: 602] [UniProtKB: Q13133]
ChEMBL	Concentration required for half maximal activity was calculated in human nuclear oxysterol receptor liver X receptor-alpha in LiSA.	B	6.6	pEC50	250	nM	EC50	J Med Chem (2001) 44: 886-897 [PMID:11300870]
GtoPdb	-	-	7.1	pEC50	-	-	-	J Biol Chem (2001) 276: 38378-87 [PMID:11504730]
GPR183 in Human [GtoPdb: 81] [UniProtKB: P32249]
GtoPdb	-	-	5.52	pEC50	3029	nM	EC50	Nature (2011) 475: 519-23 [PMID:21796211]
Liver X receptor-β in Human [GtoPdb: 601] [UniProtKB: P55055]
GtoPdb	-	-	7.15	pEC50	-	-	-	J Biol Chem (2001) 276: 38378-87 [PMID:11504730]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]