ChEMBL ligand: CHEMBL434045
Kv7.1/Voltage-gated potassium channel, IKs; KCNQ1(Kv7.1)/KCNE1(MinK) in Human [ChEMBL: CHEMBL2221347] [GtoPdb: 560] [UniProtKB: P15382, P51787] There should be some charts here, you may need to enable JavaScript!
Voltage-gated potassium channel subunit Kv7.1 in Guinea pig [ChEMBL: CHEMBL5135] [UniProtKB: O70344] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Kv7.1/Voltage-gated potassium channel, IKs; KCNQ1(Kv7.1)/KCNE1(MinK) in Human (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL2221347] [GtoPdb: 560] [UniProtKB: P15382, P51787]
GtoPdb	-	-	5	pIC50	10000	nM	IC50	J Membr Biol (2006) 210: 183-92 [PMID:16909339]; Br J Pharmacol (2001) 134: 1647-54 [PMID:11739240]
ChEMBL	Inhibition of human IKs-channel expressed in Xenopus oocytes,(Experiment 1)	B	5.3	pIC50	5000	nM	IC50	J Med Chem (2001) 44: 3831-3837 [PMID:11689069]
Voltage-gated potassium channel subunit Kv7.1 in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5135] [UniProtKB: O70344]
ChEMBL	Inhibition of guinea pig Iks potassium channel expressed in Xenopus oocytes	B	5.3	pIC50	5000	nM	IC50	J Med Chem (2004) 47: 1303-1314 [PMID:14998318]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]