ChEMBL ligand: CHEMBL15768
Acetylcholinesterase in Electrophorus electricus [ChEMBL: CHEMBL4078] [UniProtKB: O42275] There should be some charts here, you may need to enable JavaScript!
TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8] There should be some charts here, you may need to enable JavaScript!
TRPV3 in Mouse [GtoPdb: 509] [UniProtKB: Q8K424] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Acetylcholinesterase in Electrophorus electricus (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4078] [UniProtKB: O42275]
ChEMBL	Inhibition of Electrophorus electricus (electric eel) acetylcholinesterase (AChE) using acetylthiocholine iodide substrate by Ellman method based colorimetry	B	4.3	pKi	50000	nM	Ki	Ind Crops Prod (2010) 31: 284-288
TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8]
GtoPdb	-	-	4.2	pIC50	-	-	-	Mol Cell Neurosci (2006) 32: 335-43 [PMID:16829128]
TRPV3 in Mouse [GtoPdb: 509] [UniProtKB: Q8K424]
GtoPdb	Patch clamp electrophysiology	-	2	pEC50	-	-	-	Science (2005) 307: 1468-72 [PMID:15746429]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]