PIP2 [Ligand Id: 2387] activity data from GtoPdb

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  • HCN2 in Mouse [GtoPdb: 401] [UniProtKB: O88703]
Created with Highcharts 10.3.3ValuesChart context menuHCN2pKd MousepKi MousepIC50 MousepEC50 Mouse0123456Highcharts.com
  • TRPM4 in Human [GtoPdb: 496] [UniProtKB: Q8TD43]
  • TRPM4 in Mouse [GtoPdb: 496] [UniProtKB: Q7TN37]
Created with Highcharts 10.3.3ValuesChart context menuTRPM4pKd HumanpKi HumanpIC50 HumanpEC50 HumanpKd MousepKi MousepIC50 MousepEC50 Mouse0123456Highcharts.com
  • Kv7.2 in Human [GtoPdb: 561] [UniProtKB: O43526]
Created with Highcharts 10.3.3ValuesChart context menuKv7.2pKd HumanpKi HumanpIC50 HumanpEC50 Human01234Highcharts.com
  • Kv7.4 in Human [GtoPdb: 563] [UniProtKB: P56696]
Created with Highcharts 10.3.3ValuesChart context menuKv7.4pKd HumanpKi HumanpIC50 HumanpEC50 Human01234Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
HCN2 in Mouse [GtoPdb: 401] [UniProtKB: O88703]
GtoPdb - - 4.96 pEC50 10900 nM EC50 J Gen Physiol (2006) 128: 593-604 [PMID:17074978]
TRPM4 in Human [GtoPdb: 496] [UniProtKB: Q8TD43]
GtoPdb - - 5.3 pEC50 - - - EMBO J (2006) 25: 467-78 [PMID:16424899]
TRPM4 in Mouse [GtoPdb: 496] [UniProtKB: Q7TN37]
GtoPdb - - 5.2 pEC50 - - - J Biol Chem (2005) 280: 39185-92 [PMID:16186107]
Kv7.2 in Human [GtoPdb: 561] [UniProtKB: O43526]
GtoPdb - - 3.7 pEC50 - - - J Neurosci (2005) 25: 9825-35 [PMID:16251430]
Kv7.4 in Human [GtoPdb: 563] [UniProtKB: P56696]
GtoPdb - - 3.7 pEC50 - - - J Neurosci (2005) 25: 9825-35 [PMID:16251430]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.