ChEMBL ligand: CHEMBL148333
cAMP-dependent protein kinase alpha-catalytic subunit in Rabbit [ChEMBL: CHEMBL4885] [UniProtKB: Q95J97] There should be some charts here, you may need to enable JavaScript!
Myosin light chain kinase, smooth muscle in Chicken [ChEMBL: CHEMBL3062] [UniProtKB: P11799] There should be some charts here, you may need to enable JavaScript!
Plasmodium falciparum [ChEMBL: CHEMBL364] There should be some charts here, you may need to enable JavaScript!
Protein kinase Pfmrk in Plasmodium falciparum [ChEMBL: CHEMBL4090] [UniProtKB: P90584] There should be some charts here, you may need to enable JavaScript!
CNGA1 in Rat [GtoPdb: 394] [UniProtKB: Q62927] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
cAMP-dependent protein kinase alpha-catalytic subunit in Rabbit (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4885] [UniProtKB: Q95J97]
ChEMBL	Inhibitory constant against cAPK (PKA)	B	5.92	pKi	1200	nM	Ki	J Biol Chem (1996) 271: 26157-26164 [PMID:8824261]
Myosin light chain kinase, smooth muscle in Chicken (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3062] [UniProtKB: P11799]
ChEMBL	Inhibitory constant against MLCK	B	4.17	pKi	68000	nM	Ki	J Biol Chem (1996) 271: 26157-26164 [PMID:8824261]
Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364]
ChEMBL	Antimalarial activity against drug-resistant Plasmodium falciparum D6	F	4.13	pIC50	>74000	nM	IC50	Bioorg Med Chem Lett (2007) 17: 4961-4966 [PMID:17588749]
ChEMBL	Antimalarial activity against drug-resistant Plasmodium falciparum W2	F	4.43	pIC50	>37000	nM	IC50	Bioorg Med Chem Lett (2007) 17: 4961-4966 [PMID:17588749]
Protein kinase Pfmrk in Plasmodium falciparum (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4090] [UniProtKB: P90584]
ChEMBL	Inhibition of Plasmodium falciparum Pfmrk	B	4.15	pIC50	70000	nM	IC50	Bioorg Med Chem Lett (2007) 17: 4961-4966 [PMID:17588749]
CNGA1 in Rat [GtoPdb: 394] [UniProtKB: Q62927]
GtoPdb	-	-	3.5	pIC50	-	-	-	Neurosci Lett (1997) 233: 37-40 [PMID:9324234]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]