Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
ChEMBL ligand: CHEMBL333826 (Dequalinium, Dequalinium cation) |
---|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
---|---|---|---|---|---|---|---|---|
KCa2.1 in Human [GtoPdb: 381] [UniProtKB: Q92952] | ||||||||
GtoPdb | - | - | 6.4 | pIC50 | 400 | nM | IC50 |
Br J Pharmacol (2000) 129: 627-30 [PMID:10683185]; Br J Pharmacol (2000) 129: 991-9 [PMID:10696100] |
KCa2.2 in Rat [GtoPdb: 382] [UniProtKB: P70604] | ||||||||
GtoPdb | - | - | 6.8 | pIC50 | - | - | - |
Br J Pharmacol (2000) 129: 991-9 [PMID:10696100]; Eur J Pharmacol (2000) 401: 1-7 [PMID:10915830] |
KCa2.3 in Human [GtoPdb: 383] [UniProtKB: Q9UGI6] | ||||||||
GtoPdb | - | - | 4.5 | pIC50 | - | - | - | Neuropharmacology (2001) 40: 772-83 [PMID:11369031] |
CNGA1 in Human [GtoPdb: 394] [UniProtKB: P29973] | ||||||||
GtoPdb | - | - | 6.7 | pIC50 | - | - | - | J Gen Physiol (2003) 121: 37-47 [PMID:12508052] |
CNGA2 in Human [GtoPdb: 395] [UniProtKB: Q16280] | ||||||||
GtoPdb | - | - | 5.6 | pIC50 | - | - | - | J Gen Physiol (2004) 123: 295-304 [PMID:14981138] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]