ChEMBL ligand: CHEMBL196478
OT receptor/Oxytocin receptor in Human [ChEMBL: CHEMBL2049] [GtoPdb: 369] [UniProtKB: P30559] There should be some charts here, you may need to enable JavaScript!
V1A receptor/Vasopressin V1a receptor in Human [ChEMBL: CHEMBL1889] [GtoPdb: 366] [UniProtKB: P37288] There should be some charts here, you may need to enable JavaScript!
V1B receptor/Vasopressin V1b receptor in Human [ChEMBL: CHEMBL1921] [GtoPdb: 367] [UniProtKB: P47901] There should be some charts here, you may need to enable JavaScript!
V2 receptor/Vasopressin V2 receptor in Human [ChEMBL: CHEMBL1790] [GtoPdb: 368] [UniProtKB: P30518] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
OT receptor/Oxytocin receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2049] [GtoPdb: 369] [UniProtKB: P30559]
ChEMBL	Displacement of [3H]oxytocin from human OTR	B	8.9	pKi	1.26	nM	Ki	J Med Chem (2006) 49: 4159-4170 [PMID:16821776]
ChEMBL	Binding affinity to human oxytocin receptor	B	8.9	pKi	1.26	nM	Ki	Bioorg Med Chem Lett (2008) 18: 90-94 [PMID:18032036]
ChEMBL	Displacement of [3H]-oxytocin from human oxytocin receptor	B	8.9	pKi	1.26	nM	Ki	J Med Chem (2010) 53: 6525-6538 [PMID:20550119]
GtoPdb	-	-	8.9	pKi	-	-	-	J Med Chem (2005) 48: 6956-69 [PMID:16250654]
V1A receptor/Vasopressin V1a receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1889] [GtoPdb: 366] [UniProtKB: P37288]
ChEMBL	Displacement of [3H]oxytocin from human V1a vasopressin receptor	B	5.2	pKi	<6309.57	nM	Ki	J Med Chem (2005) 48: 6956-6969 [PMID:16250654]
ChEMBL	Displacement of [3H]vasopressin from human vasopressin V1a receptor	B	5.2	pKi	6309.57	nM	Ki	J Med Chem (2010) 53: 6525-6538 [PMID:20550119]
V1B receptor/Vasopressin V1b receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1921] [GtoPdb: 367] [UniProtKB: P47901]
ChEMBL	Displacement of [3H]oxytocin from human V1b vasopressin receptor	B	5.2	pKi	<6309.57	nM	Ki	J Med Chem (2005) 48: 6956-6969 [PMID:16250654]
ChEMBL	Displacement of [3H]vasopressin from human vasopressin V1b receptor	B	5.2	pKi	>6309.57	nM	Ki	J Med Chem (2010) 53: 6525-6538 [PMID:20550119]
V2 receptor/Vasopressin V2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1790] [GtoPdb: 368] [UniProtKB: P30518]
ChEMBL	Displacement of [3H]oxytocin from human V2 vasopressin receptor	B	6.2	pKi	630.96	nM	Ki	J Med Chem (2005) 48: 6956-6969 [PMID:16250654]
ChEMBL	Displacement of [3H]vasopressin from human vasopressin V2 receptor	B	6.2	pKi	630.96	nM	Ki	J Med Chem (2010) 53: 6525-6538 [PMID:20550119]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]