SRIF-28 [Ligand Id: 2020] activity data from GtoPdb

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  • MRGPRX2 in Human [GtoPdb: 157] [UniProtKB: Q96LB1]
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  • SST1 receptor in Human [GtoPdb: 355] [UniProtKB: P30872]
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  • SST2 receptor in Human [GtoPdb: 356] [UniProtKB: P30874]
  • SST2 receptor in Mouse [GtoPdb: 356] [UniProtKB: P30875]
  • SST2 receptor in Rat [GtoPdb: 356] [UniProtKB: P30680]
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  • SST3 receptor in Human [GtoPdb: 357] [UniProtKB: P32745]
  • SST3 receptor in Mouse [GtoPdb: 357] [UniProtKB: P30935]
  • SST3 receptor in Rat [GtoPdb: 357] [UniProtKB: P30936]
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  • SST4 receptor in Human [GtoPdb: 358] [UniProtKB: P31391]
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  • SST5 receptor in Human [GtoPdb: 359] [UniProtKB: P35346]
  • SST5 receptor in Mouse [GtoPdb: 359] [UniProtKB: O08858]
  • SST5 receptor in Rat [GtoPdb: 359] [UniProtKB: P30938]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
MRGPRX2 in Human [GtoPdb: 157] [UniProtKB: Q96LB1]
GtoPdb In a calcium mobilisation assay. - 5.38 pEC50 4170 nM EC50 J Biomol Screen (2013) 18: 599-609 [PMID:23396314]
SST1 receptor in Human [GtoPdb: 355] [UniProtKB: P30872]
GtoPdb - - 9.4 pKi - - - Metab Clin Exp (1996) 45: 17-20 [PMID:8769372];
Naunyn Schmiedebergs Arch Pharmacol (1998) 357: 483-9 [PMID:9650799];
Naunyn Schmiedebergs Arch Pharmacol (1999) 360: 488-99 [PMID:10598788];
Rev Physiol Biochem Pharmacol (1998) 133: 55-108 [PMID:9600011];
J Pharmacol Exp Ther (2005) 312: 332-8 [PMID:15333679];
Endocrinology (1994) 135: 2814-7 [PMID:7988476]
SST2 receptor in Human [GtoPdb: 356] [UniProtKB: P30874]
GtoPdb - - 10.2 pKi - - - Metab Clin Exp (1996) 45: 17-20 [PMID:8769372];
Naunyn Schmiedebergs Arch Pharmacol (1998) 357: 483-9 [PMID:9650799];
Naunyn Schmiedebergs Arch Pharmacol (1999) 360: 488-99 [PMID:10598788];
J Pharmacol Exp Ther (2005) 312: 332-8 [PMID:15333679];
Endocrinology (1994) 135: 2814-7 [PMID:7988476];
Eur J Pharmacol (1998) 348: 311-20 [PMID:9652348]
SST2 receptor in Mouse [GtoPdb: 356] [UniProtKB: P30875]
GtoPdb - - 9.5 pIC50 - - - Rev Physiol Biochem Pharmacol (1998) 133: 55-108 [PMID:9600011]
SST2 receptor in Rat [GtoPdb: 356] [UniProtKB: P30680]
GtoPdb - - 8.8 pKi - - - Rev Physiol Biochem Pharmacol (1998) 133: 55-108 [PMID:9600011]
SST3 receptor in Human [GtoPdb: 357] [UniProtKB: P32745]
GtoPdb - - 9.9 pKi - - - Metab Clin Exp (1996) 45: 17-20 [PMID:8769372];
FEBS Lett (1993) 321: 279-84 [PMID:8097479];
J Pharmacol Exp Ther (2005) 312: 332-8 [PMID:15333679];
Rev Physiol Biochem Pharmacol (1998) 133: 55-108 [PMID:9600011];
Endocrinology (1994) 135: 2814-7 [PMID:7988476];
Naunyn Schmiedebergs Arch Pharmacol (1998) 357: 483-9 [PMID:9650799];
Naunyn Schmiedebergs Arch Pharmacol (1999) 360: 488-99 [PMID:10598788]
SST3 receptor in Mouse [GtoPdb: 357] [UniProtKB: P30935]
GtoPdb - - 10.2 pIC50 - - - Mol Pharmacol (1993) 43: 838-44 [PMID:8100350]
SST3 receptor in Rat [GtoPdb: 357] [UniProtKB: P30936]
GtoPdb - - 9.1 pKi - - - Rev Physiol Biochem Pharmacol (1998) 133: 55-108 [PMID:9600011]
SST4 receptor in Human [GtoPdb: 358] [UniProtKB: P31391]
GtoPdb - - 9.2 pKi - - - Metab Clin Exp (1996) 45: 17-20 [PMID:8769372];
Naunyn Schmiedebergs Arch Pharmacol (1998) 357: 483-9 [PMID:9650799];
Naunyn Schmiedebergs Arch Pharmacol (1999) 360: 488-99 [PMID:10598788];
Rev Physiol Biochem Pharmacol (1998) 133: 55-108 [PMID:9600011];
J Pharmacol Exp Ther (2005) 312: 332-8 [PMID:15333679];
Endocrinology (1994) 135: 2814-7 [PMID:7988476]
SST5 receptor in Human [GtoPdb: 359] [UniProtKB: P35346]
GtoPdb - - 10.3 pKi - - - Metab Clin Exp (1996) 45: 17-20 [PMID:8769372];
J Pharmacol Exp Ther (2005) 312: 332-8 [PMID:15333679];
Rev Physiol Biochem Pharmacol (1998) 133: 55-108 [PMID:9600011];
Endocrinology (1994) 135: 2814-7 [PMID:7988476];
Eur J Pharmacol (1998) 348: 311-20 [PMID:9652348];
Naunyn Schmiedebergs Arch Pharmacol (1998) 357: 483-9 [PMID:9650799];
Naunyn Schmiedebergs Arch Pharmacol (1999) 360: 488-99 [PMID:10598788]
SST5 receptor in Mouse [GtoPdb: 359] [UniProtKB: O08858]
GtoPdb - - 9.9 pKi - - - Neuropharmacology (2000) 39: 1451-62 [PMID:10818261]
SST5 receptor in Rat [GtoPdb: 359] [UniProtKB: P30938]
GtoPdb - - 9 pKi - - - Rev Physiol Biochem Pharmacol (1998) 133: 55-108 [PMID:9600011]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.