ifetroban [Ligand Id: 1987] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL3301673 (BMS-180291, Ifetroban) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| TP receptor in Human [GtoPdb: 346] [UniProtKB: P21731] | ||||||||
| GtoPdb | - | - | 8.4 | pKi | 4 | nM | Ki | J Pharmacol Exp Ther (1993) 264: 570-8 [PMID:8437108] |
| TP receptor/Thromboxane A2 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3156] [GtoPdb: 346] [UniProtKB: P34978] | ||||||||
| ChEMBL | Inhibition of [3H]-SQ 29,548 radioligand binding to thromboxane A2 (TXA2) receptor of human platelet membranes | B | 8.39 | pKd | 4.03 | nM | Kd | Bioorg Med Chem Lett (1992) 2: 73-76 |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
