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ChEMBL ligand: CHEMBL218071 (L-798106) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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DP1 receptor/Prostanoid DP receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4427] [GtoPdb: 338] [UniProtKB: Q13258] | ||||||||
ChEMBL | Binding affinity to DP receptor | B | 6.3 | pKi | >500 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 5639-5642 [PMID:16931013] |
EP1 receptor/Prostanoid EP1 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1811] [GtoPdb: 340] [UniProtKB: P34995] | ||||||||
ChEMBL | Binding affinity to EP1 receptor | B | 4.41 | pKi | 39000 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 5639-5642 [PMID:16931013] |
EP2 receptor/Prostanoid EP2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1881] [GtoPdb: 341] [UniProtKB: P43116] | ||||||||
ChEMBL | Binding affinity to EP2 receptor | B | 4.3 | pKi | >50000 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 5639-5642 [PMID:16931013] |
EP3 receptor/Prostanoid EP3 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3710] [GtoPdb: 342] [UniProtKB: P43115] | ||||||||
ChEMBL | Binding affinity to EP3 receptor in presence of HSA | B | 8.16 | pKi | 6.9 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 5639-5642 [PMID:16931013] |
ChEMBL | Binding affinity to EP3 receptor | B | 9.22 | pKi | 0.6 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 5639-5642 [PMID:16931013] |
GtoPdb | - | - | 9.68 | pKi | 0.21 | nM | Ki |
Bioorg Med Chem (2001) 9: 1977-84 [PMID:11504634]; Am J Physiol Renal Physiol (2008) 295: F984-94 [PMID:18632791]; Br J Pharmacol (2009) 158: 372-81 [PMID:19486006] |
EP4 receptor/Prostanoid EP4 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1836] [GtoPdb: 343] [UniProtKB: P35408] | ||||||||
ChEMBL | Binding affinity to EP4 receptor | B | 6.05 | pKi | 890 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 5639-5642 [PMID:16931013] |
FP receptor/Prostanoid FP receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1987] [GtoPdb: 344] [UniProtKB: P43088] | ||||||||
ChEMBL | Binding affinity to FP receptor | B | 6.3 | pKi | >500 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 5639-5642 [PMID:16931013] |
IP receptor/Prostanoid IP receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1995] [GtoPdb: 345] [UniProtKB: P43119] | ||||||||
ChEMBL | Binding affinity to IP receptor | B | 6.3 | pKi | >500 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 5639-5642 [PMID:16931013] |
TP receptor/Thromboxane A2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2069] [GtoPdb: 346] [UniProtKB: P21731] | ||||||||
ChEMBL | Binding affinity to TP receptor | B | 6.3 | pKi | >500 | nM | Ki | Bioorg Med Chem Lett (2006) 16: 5639-5642 [PMID:16931013] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]