ChEMBL ligand: CHEMBL521784
TP receptor/Thromboxane A2 receptor in Human [ChEMBL: CHEMBL2069] [GtoPdb: 346] [UniProtKB: P21731] TP receptor in Mouse [GtoPdb: 346] [UniProtKB: P30987] There should be some charts here, you may need to enable JavaScript!
DP1 receptor in Human [GtoPdb: 338] [UniProtKB: Q13258] There should be some charts here, you may need to enable JavaScript!
DP2 receptor in Human [GtoPdb: 339] [UniProtKB: Q9Y5Y4] There should be some charts here, you may need to enable JavaScript!
EP1 receptor in Human [GtoPdb: 340] [UniProtKB: P34995] EP1 receptor in Rat [GtoPdb: 340] [UniProtKB: P70597] There should be some charts here, you may need to enable JavaScript!
EP2 receptor in Human [GtoPdb: 341] [UniProtKB: P43116] EP2 receptor in Rat [GtoPdb: 341] [UniProtKB: Q62928] There should be some charts here, you may need to enable JavaScript!
EP3 receptor in Human [GtoPdb: 342] [UniProtKB: P43115] EP3 receptor in Rat [GtoPdb: 342] [UniProtKB: P34980] There should be some charts here, you may need to enable JavaScript!
EP4 receptor in Human [GtoPdb: 343] [UniProtKB: P35408] EP4 receptor in Rat [GtoPdb: 343] [UniProtKB: P43114] There should be some charts here, you may need to enable JavaScript!
FP receptor in Human [GtoPdb: 344] [UniProtKB: P43088] FP receptor in Mouse [GtoPdb: 344] [UniProtKB: P43117] There should be some charts here, you may need to enable JavaScript!
IP receptor in Human [GtoPdb: 345] [UniProtKB: P43119] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
TP receptor/Thromboxane A2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2069] [GtoPdb: 346] [UniProtKB: P21731]
GtoPdb	-	-	7.5	pKi	-	-	-	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
ChEMBL	Displacement of [3H]SQ29548 from thromboxane A2 receptor	B	8.26	pKi	5.5	nM	Ki	J Nat Prod (1993) 56: 441-455 [PMID:8496700]
TP receptor in Mouse [GtoPdb: 346] [UniProtKB: P30987]
GtoPdb	-	-	7.2	pKi	-	-	-	Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]
DP1 receptor in Human [GtoPdb: 338] [UniProtKB: Q13258]
GtoPdb	-	-	5.9	pKi	-	-	-	Br J Pharmacol (1998) 123: 1317-24 [PMID:9579725]; Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
DP2 receptor in Human [GtoPdb: 339] [UniProtKB: Q9Y5Y4]
GtoPdb	-	-	5.5	pKi	-	-	-	Br J Pharmacol (2002) 137: 1163-72 [PMID:12466225]
EP1 receptor in Human [GtoPdb: 340] [UniProtKB: P34995]
GtoPdb	-	-	4.5	pKi	-	-	-	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP1 receptor in Rat [GtoPdb: 340] [UniProtKB: P70597]
GtoPdb	-	-	5.2	pKi	-	-	-	Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820]
EP2 receptor in Human [GtoPdb: 341] [UniProtKB: P43116]
GtoPdb	-	-	4.9	pKi	-	-	-	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP2 receptor in Rat [GtoPdb: 341] [UniProtKB: Q62928]
GtoPdb	-	-	5.1	pKi	-	-	-	Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820]
EP3 receptor in Human [GtoPdb: 342] [UniProtKB: P43115]
GtoPdb	-	-	4.9	pKi	-	-	-	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP3 receptor in Rat [GtoPdb: 342] [UniProtKB: P34980]
GtoPdb	-	-	4.79	pKi	16200	nM	Ki	Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820]
GtoPdb	-	-	6.83	pEC50	149	nM	EC50	Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820]
EP4 receptor in Human [GtoPdb: 343] [UniProtKB: P35408]
GtoPdb	-	-	5.7	pKi	-	-	-	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP4 receptor in Rat [GtoPdb: 343] [UniProtKB: P43114]
GtoPdb	-	-	5.6	pKi	-	-	-	Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820]
FP receptor in Human [GtoPdb: 344] [UniProtKB: P43088]
GtoPdb	-	-	6.6	pKi	-	-	-	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
FP receptor in Mouse [GtoPdb: 344] [UniProtKB: P43117]
GtoPdb	-	-	6	pKi	-	-	-	Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]
IP receptor in Human [GtoPdb: 345] [UniProtKB: P43119]
GtoPdb	-	-	4.2	pKi	-	-	-	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]