SDZ 64-412 [Ligand Id: 1855] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL449395 (SDZ-64-412) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| PAF receptor/Platelet activating factor receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL250] [GtoPdb: 334] [UniProtKB: P25105] | ||||||||
| GtoPdb | - | - | 7.2 | pIC50 | - | - | - | J Pharmacol Exp Ther (1988) 247: 617-23 [PMID:3183958] |
| ChEMBL | In vitro PAF antagonistic activity by determining [3H]PAF binding to the PAF-receptor of human platelets | B | 7.22 | pIC50 | 60 | nM | IC50 | J Med Chem (1993) 36: 3098-3102 [PMID:8230095] |
| ChEMBL | In vitro inhibition of [3H]PAF receptor binding to washed human platelet membranes | B | 7.4 | pIC50 | 40 | nM | IC50 | Bioorg Med Chem Lett (1993) 3: 1493-1498 |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
