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ChEMBL ligand: CHEMBL1235246 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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PAF receptor/Platelet activating factor receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL250] [GtoPdb: 334] [UniProtKB: P25105] | ||||||||
GtoPdb | - | - | 7.9 | pKi | - | - | - |
J Biol Chem (1991) 266: 20400-5 [PMID:1657923]; J Biol Chem (1996) 271: 23298-303 [PMID:8798529] |
ChEMBL | Displacement of [3H]PAF from platelet activating factor receptor in human platelets after 3 hrs | B | 9.82 | pKi | 0.15 | nM | Ki | Bioorg. Med. Chem. Lett. (2013) 23: 1834-1838 [PMID:23403082] |
GtoPdb | - | - | 8.2 | pIC50 | - | - | - | J Immunol Methods (1995) 186: 225-31 [PMID:7594622] |
ChEMBL | Displacement of [3H]PAF from platelet activating factor receptor in human platelets after 3 hrs | B | 9.55 | pIC50 | 0.28 | nM | IC50 | Bioorg. Med. Chem. Lett. (2013) 23: 1834-1838 [PMID:23403082] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]