UDP-glucuronic acid [Ligand Id: 1784] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL228057 (Uridine-5'-Diphosphoglucuronic Acid) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| P2Y14 receptor/Purinergic receptor P2Y14 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4518] [GtoPdb: 330] [UniProtKB: Q15391] | ||||||||
| ChEMBL | Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolysis | F | 6.43 | pEC50 | 370 | nM | EC50 | J Med Chem (2007) 50: 2030-2039 [PMID:17407275] |
| ChEMBL | Agonist activity at human P2Y14 receptor expressed in human COS7 cells | F | 6.43 | pEC50 | 370 | nM | EC50 | Bioorg Med Chem (2009) 17: 5298-5311 [PMID:19502066] |
| GtoPdb | - | - | 7.2 | pEC50 | - | - | - | J Pharmacol Exp Ther (2009) 330: 162-8 [PMID:19339661] |
| P2Y14 receptor in Mouse [GtoPdb: 330] [UniProtKB: Q9ESG6] | ||||||||
| GtoPdb | - | - | 7.2 | pEC50 | - | - | - | Genomics (2001) 78: 124-8 [PMID:11735218] |
| P2Y14 receptor in Rat [GtoPdb: 330] [UniProtKB: O35881] | ||||||||
| GtoPdb | - | - | 7 | pEC50 | - | - | - | Genomics (2001) 78: 124-8 [PMID:11735218] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
